UTILIZAÇÃO DE CÉLULAS-TRONCO MESENQUIMAL EM FÊMEAS BOVINAS - RELATO DE DOIS CASOS

Abstract

Embryo production in vitro is the main animal multiplication tool to increase the amount of products of a female in the genetic improvement of herds. Brazil is a world leader in this technology and has been exporting this knowledge in recent years. However, ovum pick-up (OPU) for oocyte recovery causes important ovarian lesions, which are often irreversible. This fact decreases the production of embryos and the reproductive life of a female in animal multiplication programs. Two Nellore bovine females showed higher echogenicity in the ovaries and a low index in oocyte, embryo and pregnancy production, both had a history of several OPU, all factors indicating ovarian injury. After follicular puncture, the animals were submitted to the intra-ovarian mesenchymal stem cell (MCT) application protocol and the productive results were evaluated in the following three punctures, with an interval of fifteen days between them. Subsequently the data were compared with the results of three aspirations prior to treatment with MSC. The treatment was effective in both animals resulting in improvement of the compared aspects.