ANÁLISE INTEGRADA DE DADOS GENÉTICOS E FUNCIONAIS DE SERRATIA MARCESCENS COMO BIOINSUMO: DA PROMOÇÃO DE CRESCIMENTO VEGETAL AO POTENCIAL BIOTECNOLÓGICO MULTIFUNCIONAL

Abstract

The search for more sustainable agricultural systems has stimulated the development of strategies based on the use of beneficial microorganisms associated with plants. In this context, microbial bioinputs have been increasingly investigated as alternatives to promote plant growth, improve nutrient use efficiency, and reduce the dependence on chemical inputs in agriculture. Among microorganisms with biotechnological potential in this scenario, Serratia marcescens has attracted growing attention. This bacterium is widely distributed in natural environments and is frequently associated with the rhizosphere and plant tissues. Several strains of this species exhibit traits related to plant growth promotion, including phytohormone production, phosphate solubilization, siderophore production, and ACC deaminase activity, as well as mechanisms associated with biocontrol and tolerance to environmental stresses. With the advancement of nextgeneration sequencing technologies, genomic approaches have expanded the understanding of genes and metabolic pathways involved in these functions. However, a significant gap still exists between the identification of genes potentially associated with beneficial traits and their experimental validation in biologically relevant systems. In this context, the present study aimed to conduct a systematic review of the scientific literature to integrate genomic and functional evidence related to the biotechnological potential of S. marcescens in agricultural and environmental contexts. The review followed the PRISMA protocol and searches were conducted in the Web of Science and Scopus databases. After screening and eligibility assessment, 21 articles were included in the final synthesis. The analyzed studies indicate that different strains of this species present a wide functional repertoire associated with plant growth promotion, biocontrol, stress tolerance, and degradation of environmental contaminants. Nevertheless, the literature is still dominated by genomic predictions, with relatively few studies providing experimental validation under agronomic conditions. These findings highlight the promising potential of Serratia marcescens as a multifunctional microorganism for the development of microbial bioinputs and emphasize the need for future research integrating genomic characterization, functional validation, and field evaluations.