Avaliação do efeito do glifosato em sangue periférico e mucosa bucal de lagartos Ameiva ameiva

Abstract

Glyphosate is the most widely used herbicide worldwide, but there are still controversies about its environmental safety. This study aimed to evaluate the frequency of mutagenic damage through the micronucleus test in erythrocytes and exfoliated cells of the buccal mucosa of Ameiva ameiva lizards. Fifteen animals were collected in forest fragments in Rio Verde, Goiás, Brazil anddivided into three groups of five animals for exposure to Glyphosate (130 µg/L). Oral exposure was performed by feeding contaminated coleopteran larvae, while dermal exposure was performed by spraying under the animal's body surface. The control group was not exposed to the herbicide. The results indicated an increase in the frequency of micronuclei both in the blood and in the oral mucosa of the lizards, regardless of the route of exposure. In addition to micronucleus, other different nuclear abnormalities were detected. This study provides valuable data to estimate the health risk of Ameiva ameiva lizards exposed to low concentrations of glyphosate, which may be a long-term problem for these animals. Development agency: IF Goiano